Monovisc vs Euflexxa – Which is Better?

Last Updated On: October 1, 2024

Knee osteoarthritis (OA) affects millions worldwide, with its prevalence rising due to aging populations and increasing obesity rates. This degenerative joint disease leads to pain, stiffness, and reduced mobility, significantly impacting quality of life.

Monovisc and Euflexxa are two popular viscosupplements used to manage knee OA symptoms. While Monovisc offers the convenience of a single injection, Euflexxa requires a three-injection regimen. Both aim to improve joint function and reduce pain, though their approaches and outcomes may vary.

In this article, we will explore the comparison of Monovisc vs Euflexxa, providing a comprehensive guide to help you determine which treatment might be better for you.

Key Takeaways

• Monovisc is a single-dose hyaluronic acid injection designed to relieve knee osteoarthritis (OA) pain. It offers convenience for patients seeking fewer injections and rapid relief.
• Euflexxa is a three-dose hyaluronic acid injection regimen administered weekly. It mimics the natural synovial fluid and is particularly suited for gradual symptom relief.
• Both Monovisc and Euflexxa aim to lubricate the knee joint, reduce pain, and improve mobility. However, they differ in administration protocols and duration of treatment effects.
• Monovisc may suit individuals seeking fast relief with fewer doctor visits, while Euflexxa might be preferred by those requiring consistent joint lubrication over time.
• Patient satisfaction with both treatments is high, with minimal side effects and proven effectiveness in managing knee OA.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Monovisc online, contact our sales department for more information.

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Understanding Monovisc and Euflexxa

Monovisc and Euflexxa are both hyaluronic acid-based viscosupplements commonly used to manage knee osteoarthritis (OA). These treatments aim to restore the natural lubrication in the knee joint, providing relief from pain, reducing stiffness, and improving mobility.

Monovisc is composed of highly concentrated hyaluronic acid and is administered as a single injection, making it a convenient option for patients seeking a one-time treatment.

Meanwhile, Euflexxa is a non-animal-based hyaluronic acid that closely resembles healthy synovial fluid. It requires a series of three injections over several weeks.

Administration and Treatment Protocol

Monovisc is a single-dose hyaluronic acid injection designed to provide pain relief for knee osteoarthritis. According to the Monovisc prescribing information, the recommended Monovisc dosage is 4mL, administered directly into the knee joint (intra-articular injection). 

This Monovisc knee injection is typically administered by a healthcare professional and requires no additional follow-up injections, making it a convenient option for patients who prefer a one-time treatment. After the injection, patients are advised to rest the knee for 24-48 hours and avoid high-impact activities to ensure the best results.

In contrast, Euflexxa follows a different regimen. The treatment involves three injections, each administered one week apart. The Euflexxa injection consists of 2mL of non-animal stabilized hyaluronic acid (NASHA), which mimics the natural synovial fluid in the knee.

This multi-dose regimen aims to gradually increase joint lubrication and cushioning over several weeks, offering more sustained relief. The full course of three injections typically lasts up to six months, but like Monovisc, individual results may vary.

Effectiveness and Side Effects

Monovisc uses cross-linked hyaluronic acid to mimic the natural synovial fluid in the knee joint, providing lubrication and cushioning. Clinical trials have demonstrated that Monovisc can significantly reduce pain and improve mobility. Due to its single-injection regimen, it offers a convenient option for patients. 

On the other hand, clinical studies on Euflexxa showed the treatment to significantly improve symptoms of knee osteoarthritis, with consistent patient satisfaction ratings. Like Monovisc, Euflexxa has a minimal side effect profile, with adverse reactions typically being mild and localized. 

Both treatments effectively reduce pain and improve joint function, with Monovisc offering the convenience of fewer injections and Euflexxa providing consistent effectiveness through its three-injection regimen.

Patient Satisfaction and Conclusion

People who use Monovisc and Euflexxa often feel better. Both treatments have fans, and their reviews show that they work well for knee pain.

On Monovisc

• Bel: ”When I first started with debilitating arthritis in my right knee, my orthopedic doctor tried a cortisone injection, it was useless. I went back, and he did a Monovisc injection. What a lifesaver! Knee surgery is out of the question for me. Love Monovisc!”
• Playful: “In 2016, I was in quite a bit of pain in my knees (both of them have severe osteoarthritis). I was heading towards knee surgery but got a shot of Monovisc as an alternative… a second shot due to the excellent experience from the first injection.”

On Euflexxa

• Steph2023: ”I’m bone on bone and have so many issues.. pain with my knees. It’s hard to ambulate some days without crutches..my knee pops constantly and gets stiff . I can’t do stairs. After I get my injections, my knee feels “normal,” and this lasts 6 months to a year for me! Best decision ever!! Euflexxa is def a good choice!”

Conclusion

Choosing between Monovisc and Euflexxa depends on patient preferences. Monovisc offers a single injection for those seeking fewer doctor visits, while Euflexxa involves multiple injections and closely resembles natural knee fluid. Both effectively alleviate osteoarthritis knee pain, so the decision ultimately hinges on individual health needs and treatment goals.

FAQs

1. How does Monovisc differ from Euflexxa in terms of administration?

Monovisc requires a single injection, while Euflexxa is administered in three injections over the course of several weeks.

2. Which treatment provides longer-lasting relief, Monovisc or Euflexxa?

Both treatments offer pain relief for up to six months, though individual experiences may vary depending on the severity of the osteoarthritis and overall health.

3. Can both Monovisc and Euflexxa be used for other joints besides the knee?

These injections are primarily used for knee osteoarthritis, but depending on individual cases, healthcare providers may consider them for off-label use in other joints.

4. How do I decide between Monovisc and Euflexxa for knee osteoarthritis?

Choosing between Monovisc and Euflexxa depends on your treatment goals. Monovisc is ideal for patients seeking quick relief with fewer visits, while Euflexxa provides gradual relief over multiple doses.

References

World Health Organization. Osteoarthritis. Published July 14, 2023. https://www.who.int/news-room/fact-sheets/detail/osteoarthritis 

What You Should Know About Euflexxa If You Have Knee Arthritis. Verywell Health. https://www.verywellhealth.com/what-is-euflexxa-189720