Monovisc vs Synvisc – How Do OA Treatments Compare?

Last Updated On: October 2, 2024

Hyaluronic acid injections have been shown to significantly reduce pain and improve function in patients with knee osteoarthritis (OA). These injectable treatments are gaining popularity as non-surgical options for managing osteoarthritis symptoms.

Among the leading choices are Monovisc and Synvisc, two injectable treatments designed to mimic the natural synovial fluid in the joint, providing lubrication and cushioning. However, differences in their formulation and administration schedules can impact their effectiveness and patient preferences.

This article will compare Monovisc vs Synvisc, exploring their benefits, how they work, and their potential side effects in treating osteoarthritis.

Key Takeaways

• Monovisc and Synvisc are viscosupplements commonly used to manage osteoarthritis (OA) by enhancing joint lubrication and reducing pain.
• These treatments differ in composition, with Monovisc containing high molecular weight hyaluronic acid and Synvisc consisting of Hylan G-F 20, which impacts their mechanisms of action.
• Clinical studies report varied efficacy and patient outcomes, with some patients responding better to one treatment.
• Side effect profiles for both injections are generally mild, but patients may experience swelling, pain, or discomfort at the injection site.
• Choosing between Monovisc and Synvisc should be based on a healthcare provider’s assessment, patient needs, lifestyle, and treatment goals.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Monovisc online, contact our sales department for more information.

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Understanding Viscosupplements for Osteoarthritis

Viscosupplements are injectable treatments designed to alleviate knee pain caused by osteoarthritis (OA). These injections introduce a gel-like substance that mimics the natural synovial fluid in the joint, providing essential cushioning and lubrication. By reducing friction and enhancing joint function, viscosupplements help to relieve pain and improve mobility.

Their role in OA treatment is significant, as they offer a non-surgical option for managing symptoms. Treatments such as Monovisc, which provides relief with a single injection, and Synvisc, administered in three doses over several weeks, demonstrate the versatility of viscosupplements.

These therapies make daily activities more manageable and greatly enhance the quality of life for patients, positioning viscosupplements as an essential component of comprehensive OA management.

About Monovisc

Monovisc is a single-injection treatment designed to alleviate knee osteoarthritis pain. It is made from a highly purified form of hyaluronic acid, a substance that naturally occurs in the body’s joints. This hyaluronic acid mimics the natural synovial fluid, helping to restore proper joint function.

Monovisc works by providing three key benefits:

• Cushioning: It acts as extra padding in the knee joint, protecting the bones from excessive wear and tear.
• Lubrication: It reduces joint friction, allowing smoother movement during everyday activities.
• Pain Relief: By improving joint lubrication and cushioning, Monovisc helps to significantly lower pain levels.

As an FDA-approved treatment, Monovisc is known for its safety and effectiveness. Its single-dose administration simplifies treatment, making it a convenient option for patients seeking to reduce the frequency of injections while still enjoying long-term pain relief and improved mobility.

About Synvisc

Synvisc is a viscosupplement made from hylan G-F 20, a derivative of hyaluronic acid that mimics the natural synovial fluid found in joints. Hylan G-F 20 consists of hylan A and hylan B polymers, which provide viscosity and elasticity to aid joint movement and reduce friction.

Synvisc works by enhancing the joint’s natural fluid, providing three key benefits:

• Lubrication: It improves joint movement by reducing friction between the bones.
• Cushioning: Acts as a shock absorber, helping to protect the joint from impact.
• Pain Relief: Reduces discomfort associated with osteoarthritis by improving joint function.

Unlike single-injection options like Monovisc, Synvisc requires a three-dose regimen administered over several weeks. However, it offers versatility, as it can be used in other joints, such as the shoulders, hips, and ankles. Synvisc is widely trusted for improving mobility and relieving pain for osteoarthritis patients.

Efficacy and Patient Outcomes

Monovisc is a single-injection treatment for knee osteoarthritis that provides significant pain relief and functional improvement. Clinical studies show a 65% improvement in WOMAC pain scores at week 26. Adverse reactions are generally mild, including injection site pain, swelling, or redness, with relief lasting up to six months.

Synvisc and Synvisc-One effectively reduce pain and improve function in knee osteoarthritis patients. Clinical trials have demonstrated that Synvisc effectively reduces pain and improves function in knee OA patients. Side effects are typically mild, including local allergic reactions. Both treatments restore the viscoelastic properties of synovial fluid, enhancing joint lubrication and shock absorption.

Patient-reported Outcomes and Experiences with Monovisc and Synvisc

Patient experiences offer valuable insights into how Synvisc and Monovisc knee injections perform outside the lab. People have shared their thoughts on both treatments, highlighting key differences and preferences.

On Monovisc

• M.C. Girard:”…For me, Monovisc® has worked. It provides temporary relief of my knee pain, and I take anti-inflammatories if I need to. I also do exercises to help maintain the flexibility of my knee joints, and I lost weight to relieve some of the stress on my knees. Treatment with Monovisc® has given me a good base for all of that.”

On Synvisc

• Laffytaffy:”The first week of getting this injection was hard, but as the weeks went by, the pain in my knee was slowly going away. It has been one month since getting the injection and my knee pain has diminished almost 90%.”

Before deciding between Monovisc and Synvisc, people consider how many shots they’ll need, whether the treatment fits their budget, and what others say about their own experiences.

Conclusion

Choosing between Monovisc and Synvisc depends on individual needs and treatment goals. Monovisc offers the convenience of a single injection, ideal for those seeking a streamlined treatment option. In contrast, Synvisc provides versatility with its use in multiple joints, such as the knees, shoulders, and hips.

Both treatments effectively relieve osteoarthritis pain, but the choice ultimately comes down to a patient’s specific preferences and health plan, guided by a healthcare professional’s recommendation.

FAQs

1. What are Monovisc and Synvisc, and how do they differ?

Monovisc and Synvisc are FDA-approved treatments for osteoarthritis. Monovisc requires fewer injections, while Synvisc is favored for its lower side effect frequency.

2. How does Monovisc compare to other osteoarthritis treatments like Orthovisc, Euflexxa, or Durolane?

Monovisc differs from Orthovisc, Euflexxa, and Durolane in dosage frequency and side effect profiles. Consult your doctor to determine the most suitable treatment.

3. Are there common side effects with Monovisc injections?

Monovisc may cause side effects such as pain at the injection site or allergic reactions, though these are rare.

References

Rath L. Hyaluronic acid injections for knee pain: How it could help. Arthritis Foundation. https://www.arthritis.org/health-wellness/treatment/treatment-plan/disease-management/hyaluronic-acid-injections-for-knee-pain

Joint Injections for Arthritis Pain. www.arthritis.org. https://www.arthritis.org/health-wellness/treatment/treatment-plan/disease-management/joint-injections-for-arthritis-pain 

Mayo Clinic Q and A: Treating osteoarthritis with corticosteroid injections. https://newsnetwork.mayoclinic.org. Published 2019. https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-treating-osteoarthritis-with-corticosteroid-injections/