Nucleofill vs Profhilo – Which is Better?

Last Updated On: October 14, 2024

As individuals increasingly seek youthful appearances without the downtime associated with surgical procedures, the popularity of injectables continues to grow. This trend has given rise to various products designed to rejuvenate the skin, each with unique benefits and applications.

Among the latest innovations in cosmetics are Nucleofill and Profhilo. Unlike traditional fillers, these treatments focus on improving skin quality rather than adding volume. Nucleofill boosts hydration and skin elasticity, while Profhilo enhances skin firmness and radiance. Understanding their unique benefits can help you decide which is right for you.

This article will compare Nucleofill and Profhilo in terms of their composition, effectiveness, side effects, and cost.

Key Takeaways

• Nucleofill and Profhilo are popular injectable skin rejuvenation treatments known for their ability to enhance skin quality.
• Each treatment has distinct formulations and mechanisms of action, which influence their specific benefits and applications.
• Nucleofill and Profhilo offer unique advantages, such as deep hydration and bioremodeling, tailored to different skin concerns.
• Understanding the recommended treatment protocols for each product is essential to achieve optimal results and ensure safety.
• Educating patients about expected outcomes and differences between the two treatments is crucial for making informed choices that align with their aesthetic goals.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Nucleofill online, contact our sales department for more information.

NUCLEOFILL™ STRONG

POLYMERISED POLYNUCLEOTIDE

$119.00

Tier pricing

Save 1.68%

3 or more

$117.00 each

Save 2.52%

11 or more

$116.00 each

Save 4.2%

21 or more

$114.00 each

NUCLEOFILL™ SOFT PLUS

POLYMERISED POLYNUCLEOTIDE

$106.00

Tier pricing

Save 1.89%

3 or more

$104.00 each

Save 2.83%

11 or more

$103.00 each

Save 4.72%

21 or more

$101.00 each

NUCLEOFILL™ MEDIUM PLUS

Polynucleotides

$90.00

Tier pricing

Save 1.11%

3 or more

$89.00 each

Save 2.22%

11 or more

$88.00 each

Save 3.33%

21 or more

$87.00 each

Understanding Nucleofill and Profhilo

Nucleofill is a skin rejuvenation treatment that uses natural polynucleotides to enhance skin tightness, hydration, and brightness. It is particularly effective for delicate areas such as the under-eye region, face, neck, and hands. Nucleofill improves overall skin quality and restores a youthful appearance as it boosts the skin’s natural regenerative processes.

In contrast, Profhilo is a unique treatment that employs a high concentration of hyaluronic acid, designed to hydrate the skin deeply. Unlike traditional fillers, Profhilo enhances skin moisture and elasticity, resulting in uplifted and smoother skin. It spreads evenly under the skin to improve hydration and firmness across the treated areas.

Formulation and Mechanism of Action

Nucleofill and Profhilo are advanced skin rejuvenation treatments that enhance skin quality by working deep within the skin layers. While both aim to restore a youthful appearance, they use distinct formulations and mechanisms of action to achieve their results. 

Nucleofill

• Formulation: Nucleofill utilizes natural polynucleotides, which are DNA fragments designed to stimulate the regeneration of skin cells. These components work on a cellular level to improve skin texture, firmness, and overall quality.
• Mechanism of Action: Nucleofill targets age-related loss in skin volume and elasticity by promoting collagen production, increasing skin tightness, and supporting deep tissue repair. It provides structural support and helps rebuild what is lost with age, resulting in a firmer, more youthful look.

Profhilo

• Formulation: Profhilo is composed of a high concentration of pure hyaluronic acid, unlike traditional fillers that use cross-linked HA. This unique formulation allows it to spread seamlessly under the skin.
• Mechanism of Action: Profhilo deeply hydrates the skin, enhances moisture retention, and stimulates collagen and elastin production. It provides a youthful glow and improved skin elasticity, focusing mainly on skin hydration without adding volume.

Both Nucleofill and Profhilo are administered via injections at strategic points on the face or body, with each injection targeting specific concerns. While Nucleofill rebuilds skin structure and addresses volume loss, Profhilo focuses primarily on hydrating and smoothing the skin. 

Benefits and Effectiveness

Nucleofill and Profhilo are both effective treatments for achieving younger, more hydrated skin. Each addresses different needs with unique benefits.

Nucleofill improves skin texture and boost firmness by stimulating collagen and elastin production. This treatment effectively reduces wrinkles and enhances moisture levels, making it safe for various facial areas, including around the eyes. Patients often experience fresher, brighter skin shortly after treatment, with minimal post-care required.

Profhilo works by enhancing hydration from within by slowly releasing hyaluronic acid, smoothing fine lines, and revitalizing the skin’s appearance. Patients typically see noticeable results within days, requiring only two sessions a month apart. Initial improvements can be observed after the first session, with full benefits around four weeks after the second. It stimulates collagen production for firmer skin with few side effects.

Nucleofill and Profhilo offer innovative solutions for skin rejuvenation, catering to different needs. With their unique mechanisms and minimal downtime, these treatments provide patients with effective options for achieving healthier, more youthful skin, making them popular choices among practitioners and clients alike.

Treatment Protocols and Expected Results

The treatment protocols for Nucleofill and Profhilo involve specific approaches to achieve optimal skin rejuvenation. Each product offers unique benefits, and adhering to proper protocols ensures maximum effectiveness.

Nucleofill is typically administered in multiple sessions, spaced two to four weeks apart. The treatment targets areas such as the under-eye, cheeks, and neck, focusing on regenerating skin tissue and boosting collagen production. Nucleofill before and after photos often show significant improvements in skin elasticity, reduction in fine lines, and a firmer appearance after the full course of treatments.

Patients usually need three to four sessions to achieve the desired results, and maintenance sessions are recommended annually to sustain the effects.

Meanwhile, Profhilo is administered in two initial sessions, spaced four weeks apart. The injection technique involves five strategic points on each side of the face, known as the BAP (Bio Aesthetic Points), to maximize the distribution of hyaluronic acid. The results are generally visible after the first session, with improved hydration, elasticity, and an overall glow.

The before and after outcomes of Profhilo typically show enhanced skin radiance and smoothness, with effects lasting up to six months. Regular maintenance sessions are also recommended twice a year.

Expected Results

Both treatments provide visible skin rejuvenation, but their effects differ based on their mechanisms. Nucleofill works primarily on restoring lost volume and elasticity, promoting a stronger, firmer skin structure. In contrast, Profhilo improves hydration and smoothness, creating a radiant, dewy appearance.

Conclusion

Nucleofill and Profhilo each offer distinct advantages for skin rejuvenation. Their specific formulations and mechanisms address unique aesthetic needs. By understanding the treatment protocols and expected results, individuals can make an informed choice about which option best suits their skin concerns.

Consulting with a qualified practitioner is essential to determine the right approach, ensure a customized treatment plan, and achieve the best possible results in skin health and rejuvenation.

FAQs

1. What is the difference between Nucleofill and Profhilo?

Nucleofill and Profhilo are both treatments used for skin rejuvenation but have different injection points and aftercare protocols.

2. Are there any side effects to using Nucleofill?

Yes, like most treatments, Nucleofill can have side effects. However, it’s best to discuss these with your healthcare provider who can provide detailed information.

3. How many sessions of Nucleofill are typically recommended?

One to three sessions of Nucleofill are typically recommended, spaced a few weeks apart for optimal results.

4. Can I use Nucleofill for my eyes?

While some people may consider using Nucleofill for their eyes due to its rejuvenating properties, as this area is susceptible, always consult a professional first.

References

Cosmetic & Medical injectables overview. News-Medical. https://www.news-medical.net/health/Cosmetic-Medical-Injectables-Overview.aspx

Department of Health & Human Services. Cosmetic treatments – injectables. Better Health Channel. https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/cosmetic-treatments-injectables