Nucleofill vs Rejuran – Comparing Treatments

Last Updated On: October 14, 2024

In 2020, over 13.3 million minimally invasive cosmetic procedures were performed, according to the American Society of Plastic Surgeons. This rise reflects the growing popularity of treatments that deliver quick results with minimal downtime. Among these, skin boosters have gained significant attention for effectively improving skin hydration and texture.

Nucleofill and Rejuran are two leading injectable treatments in the market today. Nucleofill is known for its deep hydration and collagen-boosting properties, while Rejuran harnesses the power of salmon DNA to promote skin repair and regeneration. Although both treatments enhance skin health and appearance, they work through distinct mechanisms, offering unique benefits.

This article will compare Nucleofill vs Rejuran, delving into their key features, benefits, and differences to help you determine which treatment is best suited to your skin concerns.

Key Takeaways

• Nucleofill and Rejuran are innovative skin rejuvenation treatments that use unique active ingredients to enhance skin health, texture, and appearance.
• Nucleofill utilizes a high concentration of polynucleotides to boost collagen and elastin production, improving skin hydration, elasticity, and quality. This makes it ideal for more pronounced rejuvenation.
• Rejuran harnesses polynucleotides derived from salmon DNA to repair damaged skin cells, promote collagen production and reduce wrinkles, which makes it particularly effective for skin healing.
• Choosing between Nucleofill and Rejuran depends on individual skin concerns. Nucleofill provides deeper hydration, while Rejuran focuses more on skin repair and regeneration.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Nucleofill online, contact our sales department for more information.

NUCLEOFILL™ STRONG

POLYMERISED POLYNUCLEOTIDE

$119.00

Tier pricing

Save 1.68%

3 or more

$117.00 each

Save 2.52%

11 or more

$116.00 each

Save 4.2%

21 or more

$114.00 each

NUCLEOFILL™ SOFT PLUS

POLYMERISED POLYNUCLEOTIDE

$106.00

Tier pricing

Save 1.89%

3 or more

$104.00 each

Save 2.83%

11 or more

$103.00 each

Save 4.72%

21 or more

$101.00 each

NUCLEOFILL™ MEDIUM PLUS

Polynucleotides

$90.00

Tier pricing

Save 1.11%

3 or more

$89.00 each

Save 2.22%

11 or more

$88.00 each

Save 3.33%

21 or more

$87.00 each

Understanding Nucleofill and Rejuran Treatments

Nucleofill and Rejuran are innovative skin rejuvenation treatments, each offering distinct benefits through unique active ingredients to enhance skin health, texture, and appearance.

• Nucleofill: This treatment uses a high concentration of polynucleotides to boost collagen and elastin production, enhancing skin hydration, quality, and texture for a more youthful look.
• Rejuran: Rejuran utilizes polynucleotides derived from salmon DNA to promote skin healing, improve elasticity, and reduce wrinkles through increased collagen production.

While both treatments aim to improve skin texture and hydration, they differ in their active ingredients and mechanisms. Nucleofill’s higher polynucleotide concentration may result in more pronounced rejuvenation effects, making it a popular choice for those seeking vibrant, youthful skin.

Mechanism of Action

Nucleofill enhances skin elasticity and hydration through the use of high concentrations of polynucleotides, which stimulate collagen and elastin production to create a fresh, youthful appearance. This mechanism targets the underlying causes of aging by boosting the skin’s natural regenerative processes.

In contrast, Rejuran works by repairing damaged skin cells using polynucleotides derived from salmon DNA. This promotes collagen production, leading to improved skin texture and reduced wrinkles. Rejuran’s compatibility with human skin results in minimal side effects, making it suitable for all skin types seeking rejuvenation.

While both treatments aim to revitalize the skin, Nucleofill’s higher polynucleotide concentration may offer a slight edge in rejuvenation, emphasizing their roles in effective anti-aging strategies.

Suitable Treatment Areas

Nucleofill and Rejuran address different skin concerns, each offering unique benefits. Nucleofill injection points include the face, neck, and decollete, providing deep hydration and enhancing moisture and tightness, especially around the eyes. Nucleofill effectively improves skin quality and firmness by boosting collagen production, making it ideal for aging areas.

Rejuran promotes healing and collagen production, effectively targeting fine lines around the eyes, mouth, and forehead. It is also effective on the hands, improving texture and tightness. Both treatments enhance collagen production; however, Nucleofill’s higher polynucleotide concentration provides additional rejuvenation benefits, particularly for the hands and decollete.

Patient Outcomes and Clinical Data

The patient underwent Nucleofill treatment around the eyes, which resulted in noticeable improvements in hydration and skin tightness. Before-and-after images highlight rejuvenated, firmer skin with reduced signs of aging.

Image courtesy of Nucleofill Moldova

The patient sought eye rejuvenation with Rejuran to address dark circles, dry skin, and fine lines. Images were taken after medical consultation and treatment, with consent documented.

Image courtesy of Aescar Clinic

Clinical Data 

Clinical data on Nucleofill and Rejuran highlight their effectiveness in enhancing skin quality, improving hydration, and promoting collagen production, demonstrating significant benefits for various skin concerns and rejuvenation needs.

Nucleofill is a skin injectable treatment designed for deep skin renewal and bio-stimulation. It works on three levels: skin lifting, antioxidation, and hydration. Clinical validation has shown its effectiveness in achieving clear, revitalized skin.

According to a randomized, participant and evaluator-blinded study comparing polycaprolactone and polynucleotide fillers for the correction of crow’s feet, Rejuran effectively improved skin texture and elasticity. The study highlighted Rejuran’s regenerative properties, making it a popular choice for skin rejuvenation.

Conclusion

Nucleofill and Rejuran are designed to enhance skin health by stimulating collagen production. While Nucleofill contains a higher concentration of active ingredients, which may offer enhanced results for some individuals, both treatments cater to different skin needs and target areas.

Ultimately, choosing between them depends on each person’s unique skin concerns and desired outcomes.

FAQs

1. How long do the effects of Nucleofill last?

The effects of Nucleofill typically last between six to twelve months, depending on individual skin conditions and care.

2. Is Nucleofill suitable for all skin types?

Yes, Nucleofill is generally suitable for all skin types, but a consultation with a healthcare provider is recommended to assess individual suitability.

3. What should I expect during a Nucleofill treatment session?

During a Nucleofill treatment session, you can expect a minimally invasive procedure where the solution is injected into the targeted areas of your skin. The treatment is generally well-tolerated, with most patients experiencing only mild discomfort.

4. What precautions should I take after receiving Nucleofill treatment?

After receiving Nucleofill treatment, avoiding excessive sun exposure and using sunscreen to protect your skin is vital. Additionally, refrain from applying makeup or engaging in strenuous activities for at least 24 hours.

References

American Society of Plastic Surgeons. PLASTIC SURGERY STATISTICS REPORT 2020.; 2020. https://www.plasticsurgery.org/documents/News/Statistics/2020/plastic-surgery-statistics-full-report-2020.pdf 

Edgar J. The 7 Buzziest Cosmetic Treatment Launches of 2022. RealSelf News. Published December 28, 2021. Accessed October 2, 2024. https://www.realself.com/news/cosmetic-treatment-launches-2022