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Synvisc Ingredients – About Hylan A and Hylan B Polymers

David Fuller

Last Updated On: August 8, 2024

Did you know joint lubrication is crucial in maintaining mobility and reducing pain? Experts have highlighted that adequate joint lubrication is essential for smooth movement, especially in weight-bearing joints like the knees. When lubrication diminishes due to conditions like osteoarthritis, discomfort, and stiffness can limit daily activities.

Synvisc is a remarkable solution for knee osteoarthritis. Synvisc is a unique intra-articular injection containing hylan A and hylan B polymers derived from chicken combs. These hylans are chemically crosslinked, making Synvisc an elastoviscous high molecular weight fluid. Hylan A and hylan B mimic the natural synovial fluid, providing lubrication and cushioning within the knee joint.

In this article, we will examine Synvisc’s ingredients, focusing on Hylan A and Hylan B polymers, their formulation, and their roles in treating osteoarthritis. 

Key Takeaways

  • Hylan A and Hylan B polymers are key ingredients in Synvisc, a treatment for osteoarthritis.
  • These polymers are derived from hyaluronic acid and are crucial in lubrication and cushioning to the joints.
  • Scientific evidence supports the effectiveness and safety of Hylan A and Hylan B polymers in treating osteoarthritis, offering pain relief and improved joint mobility.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Synvisc online, contact our sales department for more information.

What are Hylan A and Hylan B Polymers?

Hylan A and Hylan B are key ingredients in Synvisc, derived from hyaluronic acid, which is naturally found in joint fluids. Hyaluronic acid provides lubrication and cushioning to joints. In Synvisc, hyaluronic acid is chemically modified to create larger Hylan A and Hylan B polymers. These polymers more effectively mimic the natural joint fluid lost due to osteoarthritis, enhancing joint lubrication and cushioning.

Synvisc aims to alleviate pain and improve joint mobility by restoring this balance. Its polymers, with their ability to bind water and mimic natural joint fluid, offer long-lasting relief compared to traditional treatments. Many patients report significant pain reduction and improved movement after receiving Synvisc injections, highlighting its effectiveness in managing joint issues.

Scientific Basis for Using Hylan A and Hylan B Polymers in Synvisc

Synvisc (Hylan G-F 20) has been extensively studied for its efficacy and safety in treating knee osteoarthritis (OA). Clinical trials have demonstrated that Synvisc can provide up to six months of relief for chronic knee OA pain, with a significant reduction in pain at 12 months compared to other viscosupplements.

This validation emphasizes the safety and enduring benefits of using Hylan A and B polymers for effective joint health management.

Benefits of Hylan A and Hylan B Polymers in Synvisc

Hylan A and Hylan B Polymers in Synvisc help make painful joints feel better and move more easily.

  • Pain Relief in Osteoarthritic Joints: Hylan A and B in Synvisc mimic natural joint fluid, providing cushioning and reducing pain in osteoarthritic joints. This leads to less discomfort and improved mobility. Patients often experience significant pain relief compared to other treatments like Monovisc or Orthovisc, allowing them to engage in daily activities with less pain. 
  • Improvement in Joint Mobility and Function: Synvisc’s Hylan A and B polymers enhance joint lubrication and cushioning, improving mobility and function in osteoarthritic joints. Patients frequently report easier movement and reduced stiffness after treatment. Compared to alternatives like Monovisc or Orthovisc, Synvisc provides long-lasting support, making daily activities more manageable and reducing pain. This improved function significantly boosts overall quality of life.
  • Long-Lasting Effects Compared to Traditional Treatments: Unlike traditional treatments, Synvisc’s effects often last longer, reducing the need for frequent injections. Patients typically experience sustained pain relief and increased satisfaction, allowing them to maintain an active lifestyle with fewer interruptions.

Safety and Effectiveness of Hylan A and Hylan B Polymers

Studies show Hylan A and B polymers are safe for treating joint pain. Many patients see good results without major side effects.

  • Fewer Allergic Reactions: Synvisc shows fewer allergic reactions than Hyalgan, enhancing patient safety.
  • Lower Risk of Swelling: Patients report less swelling with Synvisc than with Monovisc or Orthovisc.
  • Minimal Injection Site Pain: Synvisc causes significantly less pain at the injection site compared to alternatives.
  • High Tolerance Among Patients: Synvisc is well-tolerated by patients, making it a preferred choice.
  • Satisfactory Side Effect Profile: Clinical data shows Synvisc has a favorable side effect profile compared to other treatments.
  • Positive Feedback from Medical Professionals: Doctors favor Synvisc for its proven effectiveness and safety.
  • Broad Acceptance in Clinical Practice: Synvisc is widely used in medical practice for its strong safety profile.

Patient Satisfaction

Doctors and patients report high satisfaction with Synvisc, noting significant pain relief and improved mobility in osteoarthritis. Synvisc for shoulder and knee is preferred for its lasting effects and fewer side effects. Positive patient experiences and effective symptom management highlight Synvisc’s advantages.

Conclusion

Hylan A and Hylan B polymers in Synvisc provide effective pain relief and improved joint movement, often with longer-lasting results than other treatments. Users report increased activity and satisfaction, and safety data supports its efficacy. Synvisc’s ingredients make it a reliable option for managing joint pain.

FAQs

1. What are the ingredients in Synvisc?

Synvisc is a medical treatment primarily containing Hylan A and Hylan B polymers.

2. Are there any side effects of using Synvisc?

Yes, like all medications, Synvisc may have side effects. It’s always best to consult with your doctor or pharmacist for detailed information.

3. How does Synvisc compare to Monovisc and Orthovisc?

Synvisc, Monovisc, and Orthovisc are all treatments for joint pain, but they differ in their composition and application methods. Your healthcare provider can provide more specific comparisons based on your individual needs.

4. Is it essential to know about the ingredients of Synvisc before use?

Yes! Understanding the ingredients like Hylan A and B polymers helps you be aware of potential reactions or side effects.

References

SYNVISC® HYLAN G-F 20 Prescribing Information. products.sanofi.us. https://products.sanofi.us/synvisc/synvisc.html 

Synvisc-One (Hylan G-F 20 Single Intra-articular Injection): Side Effects, Uses, Dosage, Interactions, Warnings. RxList. Accessed August 1, 2024. https://www.rxlist.com/synvisc-one-drug.htm 

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