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Mesotherapy

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Mesotherapy involves using multiple intradermal or subcutaneous injections of a mixture of compounds, administered in minute doses through very fine needles.

What Are Mesotherapy Injections Used For?

Mesotherapy does not refer to a treatment of a particular condition. Rather, it simply describes a method of drug delivery involving multiple intradermal or subcutaneous injections of a mixture of compounds in minute doses to treat cosmetic conditions.

Mesotherapy injections have a range of applications, including: 

  • Fat removal in areas like the stomach, thighs, hips, buttocks, arms, legs, and face 
  • Cellulite reduction
  • Wrinkle and fine-line treatment
  • Tightening loose skin 
  • Contouring and shaping the body 
  • Bio-rejuvenation
  • Lightening pigmented skin
  • Alopecia treatment

The injection composition varies depending on the exact treatment. It is often a mixture of various compounds, such as plant extracts, homeopathic agents, pharmaceuticals, vitamins, and other bioactive substances. 

How Long Do Mesotherapy Injections Last?

Mesotherapy injections typically last between 12 and 18 months. However, top-up or maintenance sessions are required about once every three to six months to maintain results.

Types of Mesotherapy Injections

There are many types of mesotherapy injections, such as:

  • Mesowhite for reducing sun damage, age spots, and hyperpigmentation 
  • Meso-drainage for reducing cellulite by breaking down fatty deposits 
  • Lipolysis for reducing cellulite by eliminating localized fat deposits 
  • Hair mesotherapy for stimulating hair growth to counter hair loss and hair thinning 
  • Mesolift for rejuvenating, hydrating, and tightening skin in the face, neck, and decolletage 

Mesotherapy Injections Brands

Popular mesotherapy injection brands and products include:

BCN ADIPO FORTE 

BCN ADIPO FORTE is an anti-cellulite designed to get rid of localized fat deposits from the body contour and abdominal folds, and from the upper arms, thighs, buttocks, and knees. It also redefines the body’s silhouette and strengthens the skin, minimizing the appearance of uneven skin texture. 

PRX-T33® 

PRX-T33® (WiQo®) is a bio-revitalizer that stimulates dermal biostimulation without harming the skin. It is not a chemical peel and causes no frosting or desquamation after treatment owing to its formulation, which combines hydrogen peroxide (H2O2) and trichloroacetic acid (TCA). 

It is typically used for the treatment of facial and décolletage skin elastosis, prevention of scar hypertrophy, and treatment of melasma and post-inflammatory hyperpigmentation

JALUPRO®

JALUPRO® SUPER HYDRO is a sterile re-absorbable injectable solution that acts as a unique deep bio-revitalization treatment, combined with biopeptides and a high concentration of high and low molecular weight hyaluronic acid.

It acts in the deep connective tissue, strengthening the synthesis of collagen and elastin in the dermis, countering the signs of aging, and correcting imperfections and minor defects in the skin. It is sold as a pre-filled syringe containing amino acids (glycine, L-proline, L-leucine, L-lysine), biopeptides, and hyaluronic acid.

Mesotherapy Injections Administration Technique

Mesotherapy sessions typically involve superficial injections using specialized short needles directly over the site of affected structures. 

Several hundred injections are given, though the number varies from procedure to procedure. For conditions such as cellulite, 10-15 sessions are required, with maintenance scheduled every six months or a year. 

There are three different techniques used in mesotherapy treatments: 

  1. Point by point—This involves injections of 0.02 ml to 0.05 ml of drug solution given one to two centimeters apart, four milimeters deep, and perpendicular to the skin 
  2. Nappage—This involves more superficial (two milimiters deep) injections administered with a four milimeter needle covering a large area. Injections are administered at a 45-degree angle to the skin while applying constant light pressure on the plunger. At each injection site, a drop of solution is introduced while the practitioner repeatedly flicks the wrist, mimicking a salt shaker 
  3. Epidermic—This technique involves the most superficial (one milimeter deep) injections where the basal layer is not penetrated. A needle size of 27 to 31 gauge is used with the bevel oriented away from the skin and light, positive pressure applied to the plunger. The solution is administered in a grid pattern at one centimeter intervals over a large affected area

Each technique involves multiple injections of small doses in precise locations, which can be a highly demanding procedure for the practioner. For this reason, many practitioners use a device called a mesogun or a special technique called meso-perfusion, which guarantees faster injections, precise dose delivery, consistent penetration depth, and better comfort for the physician and patient. 

Mesotherapy Injections Side Effects

Side effects associated with mesotherapy include: 

  • Nausea and vomiting 
  • Diarrhea 
  • Minor pain in treated areas 
  • Edema
  • Itching 
  • Erythema 
  • Skin hyperesthesia
  • Tender subcutaneous nodules at the injection site

Some pigmentation problems may occur, including post-inflammatory hyperpigmentation and urticaria pigmentosa, which may remain for many months. In rare cases, full-thickness skin and fatty tissue necrosis have also occurred.

In addition, adverse effects due to a faulty administration technique can be serious and include:

  • Localized infections
  • Permanent scarring 
  • Subcutaneous nodules
  • Nontuberculous mycobacterial skin infections
  • Transmission of infections (AIDS, Hepatitis B, Hepatitis C) associated with improper needle use

Some patients may experience hypersensitivity reactions (especially to hyaluronidase and collagenase), resulting in immediate or delayed pruritic, maculopapular rash distant from the treated area.

To reduce the risk of adverse side effects, it’s essential to follow the proper administration technique and buy mesotherapy injections from trusted sellers. For guidance on buying mesotherapy injections safely, contact our experts at Med Supply Solutions.

Frequently Asked Questions 

Is Mesotherapy Painful?

No, patients may experience a slight pinching or burning sensation when the treatment is being administered, but it is not painful as the injections are administered superficially. 

Does Mesotherapy Work Immediately?

Mesotherapy does not give immediate results. Treatment requires several sessions spread out over a couple of weeks before patients begin to see visible results. 

What Is the Difference Between Prp and Mesotherapy for Skin?

Mesotherapy involves injecting hair-growth vitamins and minerals into the scalp, while PRP involves injecting platelet-rich plasma. 

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