RESTYLANE® DEFYNE™ is an injectable, viscoelastic gel containing non-animal, cross-linked hyaluronic acid and Lidocaine, for pain relief. RESTYLANE® DEFYNE™ is suitable for use as a dermal filler to correct deep wrinkles, folds, or other skin defects when injected into the deep dermis or upper subcutaneous layer. Results of an RESTYLANE® DEFYNE™ treatment usually last about six to nine months, and sometimes as long as twelve months. Only authorized personnel, in accordance with local legislation, should administer RESTYLANE® DEFYNE™.

Quantity Price
1 - 5 $209.00
6 - 10 $199.00
11 - 20 $194.00
21+ $189.00

How can I purchase RESTYLANE® DEFYNE™?

RESTYLANE® DEFYNE™ is a dermal filler made of hyaluronic acid that provides a high level of volume to the skin. You can buy RESTYLANE® DEFYNE™ online from or you can phone our friendly customer service team to order this and other dermal fillers. When you order wholesale RESTYLANE® DEFYNE™ from Med Supply Solutions, you can help smooth the look of deep wrinkles to give your patients more youthful-looking skin.

Why is RESTYLANE® DEFYNE™ different from other dermal fillers?

Many dermal fillers use non-cross-linked hyaluronic acid to adjust the thickness of their product, but it can degrade quickly without providing a filling effect. However, RESTYLANE® DEFYNE™ adjusts its formula without using free hyaluronic acid. The makers of EMERVEL® use Optimal Balance Technology™ to adjust the level of cross-linking in their products, creating a softer or firmer gel for different applications. They also pass the EMERVEL® gel through different sizes of mesh to sort out particle sizes, using the larger particles and firmer gel for deeper dermal fillers like RESTYLANE® DEFYNE™.

Where can I inject RESTYLANE® DEFYNE™?

You should inject RESTYLANE® DEFYNE™ into the deep dermis or the upper subcutaneous layer. With its particular particle size, RESTYLANE® DEFYNE™ is suitable for injections into deep wrinkles and folds, including marionette lines that run from the mouth to the chin and nasolabial folds that run between the nose and the mouth. RESTYLANE® DEFYNE™ can help fill these deep skin defects to give the skin a smoother appearance.

When does RESTYLANE® DEFYNE™ give visible results?

Like other dermal fillers made with hyaluronic acid, RESTYLANE® DEFYNE™ gives your patients immediate results. As you inject RESTYLANE® DEFYNE™ into the deep dermis or subcutaneous layer, the hyaluronic acid binds moisture to provide volume within the skin. This fills in deep wrinkles and folds and supports the top layers of skin, giving the skin a smoother appearance. The results of a RESTYLANE® DEFYNE™ treatment can last for about six to nine months, and sometimes even twelve months. As the results of an RESTYLANE® DEFYNE™ injection start to fade, your patients can return for another treatment to maintain their smooth skin.

What are the side effects of RESTYLANE® DEFYNE™ treatments?

Common RESTYLANE® DEFYNE™ side effects include skin redness or erythema, itching, swelling, mild pain and tenderness, although these side effects usually disappear within a few days after the injection. You should not inject RESTYLANE® DEFYNE™ into areas where there is already a permanent or temporary dermal filler. Contraindications of RESTYLANE® DEFYNE™ injections include use in areas with chronic or acute skin lesions, use on pregnant or breastfeeding women, and use on patients who have porphyria, an autoimmune disorder, severe allergies, or a hypersensitivity or allergy to hyaluronic acid, Lidocaine, or the amide anesthetics that are found in Lidocaine formulas.

Who should purchase RESTYLANE® DEFYNE™?

If you have patients who have deep wrinkles and severe facial folds, you should purchase RESTYLANE® DEFYNE™ for your dermatology or plastic surgery clinic. RESTYLANE® DEFYNE™ can effectively fill these deep skin defects, such as nasolabial folds and marionette lines, with less chance of swelling, redness, and other side effects according to clinical studies. Order wholesale RESTYLANE® DEFYNE™ from Med Supply Solutions to help give your patients smoother skin for a more youthful appearance.

Information about this product that is provided by is only summary, and does not cover all of the information about this product.


* Med Supply Solutions offers only genuine RESTYLANE® DEFYNE™ that is manufactured by Galderma. All brands listed here including RESTYLANE® DEFYNE™ are the trademarks of their respective owners. Med Supply Solutions is not operated by, supported by or affiliated with Galderma.



Active Substance(s)

Hyaluronic acid, lidocaine


20mg/ml, 3mg/ml

Pack Size

1-1ml prefilled syringe


Package insert, 2-27G 1/2” needles, 2 traceability labels



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